SKLB 4771
SKLB4771
CAS: 1370256-78-2
Molecular Formula: C25H27N7O3S2
SKLB 4771 - Names and Identifiers
| Name | SKLB4771 |
| Synonyms | AOB5016 SKLB477 SKLB4771 FLT3-IN-1 SKLB-4771 SKLB 4771 CHEMBL2046883 1-(5-(7-(3-morpholinopropoxy)quinazolin-4-ylthio)-1,3,4-thiadiazol-2-yl)-3-p-tolylurea N-(4-Methylphenyl)-N'-[5-[[7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]thio]-1,3,4-thiadiazol-2-yl]urea |
| CAS | 1370256-78-2 |
SKLB 4771 - Physico-chemical Properties
| Molecular Formula | C25H27N7O3S2 |
| Molar Mass | 537.66 |
| Density | 1.43±0.1 g/cm3(Predicted) |
| Solubility | DMSO: ≥ 47 mg/mL |
| pKa | 6.62±0.50(Predicted) |
| Storage Condition | -20℃ |
SKLB 4771 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.86 ml | 9.3 ml | 18.599 ml |
| 5 mM | 0.372 ml | 1.86 ml | 3.72 ml |
| 10 mM | 0.186 ml | 0.93 ml | 1.86 ml |
| 5 mM | 0.037 ml | 0.186 ml | 0.372 ml |
Last Update：2024-01-02 23:10:35
SKLB 4771 - Reference Information
| biological activity | SKLB4771 is a potent and selective human receptor tyrosine protein kinase FLT3 inhibitor, the IC50 was 10 μm. |
| Target | Value |
| FLT3 (Cell-free assay) | 10 nM |
Last Update：2024-04-09 20:45:29
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Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
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View History
SKLB 4771
(R)-(-)-联萘酚磷酸酯
2,8a(1H,6H)-Isoquinolinedicarboxylic acid, 3,4,7,8-tetrahydro-6-oxo-, 2-(1,1-dimethylethyl) 8a-methyl ester, (8aR)-
(4R)-7-Fluoro-3,4-dihydro-2H-1-benzopyran-4-amine hydrochloride
Imidazo[1,2-a]quinoxaline, 1-bromo-4-chloro-
Ethanone,1,1'-[1,2-ethanediylbis(6-hydroxy-6-methyl-3-nitro-3,1-cyclohexanediyl)]bis- (9CI)
(2R,3R,4S,5S,6R)-2-(庚氧基)-6-(羟甲基)四氢-2H-吡喃-3,4,5-三醇
(R)-(-)-联萘酚磷酸酯
2,8a(1H,6H)-Isoquinolinedicarboxylic acid, 3,4,7,8-tetrahydro-6-oxo-, 2-(1,1-dimethylethyl) 8a-methyl ester, (8aR)-
(4R)-7-Fluoro-3,4-dihydro-2H-1-benzopyran-4-amine hydrochloride
Imidazo[1,2-a]quinoxaline, 1-bromo-4-chloro-
Ethanone,1,1'-[1,2-ethanediylbis(6-hydroxy-6-methyl-3-nitro-3,1-cyclohexanediyl)]bis- (9CI)
(2R,3R,4S,5S,6R)-2-(庚氧基)-6-(羟甲基)四氢-2H-吡喃-3,4,5-三醇